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Ethics declarations Competing interests Throughout the development of GLP-1RAs, J.J.H

Evidencia 2026 Datos clnicos Evidencia 2026 Datos clnicos Datos de Fase 2 (LY3437943) El ensayo Fase 2 LY3437943 (Jastreboff et al., NEJM 2023) evalu Retatrutida en mltiples brazos de dosis durante 48 semanas en adultos con obesidad sin DM2

How Far We Need to Go

Tirzepatide for Weight Loss: What It Is and Who Its For Tirzepatide was approved by the FDA in 2022 for type 2 diabetes, and in 2023 for weight control for people with obesity or overweight and at least one weight-related condition (like high blood pressure or cholesterol)

However, these concerns are controversial in clinical trials

[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Toshinai K, Date Y, Murakami N, Shimada M, Mondal MS, Shimbara T, Guan JL, Wang QP, Funahashi H, Sakurai T, et al