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Description
Clinical trials (ten studies, 419 participants) using doses from 400 mg to 10 g over 21 days to 20 months show consistent reductions in fasting glucose, post-meal glucose, and HbA1c. In diabetic animal studies, gymnema increased proglucagon gene expression (a precursor for GLP-1) and insulin gene activity, suggesting it may help amplify endogenous GLP-1 production
however, they can also lead to nutrient depletion
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The results revealed that confirmed NAION cases were extremely rare, with only three cases in the treated group and five cases in the placebo group.
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