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Underwood et al., 2013

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In breast cancer, metastatic progression occurred in 10.2% of GLP-1RA-exposed patients compared with 20.1% of matched DPP-4 inhibitor controls, corresponding to a 43% relative reduction in progression risk (HR, 0.57

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It found that saxagliptin significantly increased the risk of HF by 21%, especially in patients at high risk for cardiovascular, while no signal was detected for other DPP4i

Gymnemic acids curb the binding of carbohydrates to the receptors in the intestine and hence, the empty calories are taken care of so that the body does not go into obese stage