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Nausea and slower gastric emptying can mimic or amplify reflux sensations, making it difficult to distinguish between true acid exposure and medication adjustment effects

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Reference Sorli, Harashima, Tsoukas, Unger, Karsbl and Hansen19Reference Kavarian, Mosher and Abu El Haija24 An additional effect of the GLP-1 receptor agonist (GLP-1 RA) is reduction of appetite and energy intake with a reduction in body weight

Retatrutide is an investigational peptide that acts as a triple agonist at GIP, GLP-1, and glucagon receptors, currently in clinical development for obesity and type 2 diabetes (Jastreboff et al