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Follow-up Duration : While trials extend to 72 weeks or longer, the chronic nature of obesity requires decades-long, unavailable safety and efficacy data

Semaglutide is a GLP-1 receptor agonist that reduces appetite and promotes weight loss through central and peripheral mechanisms

Personalized care should consider both hormonal and metabolic factors to optimize symptom management

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The added glucagon receptor activation increases energy expenditure and fat oxidation, which likely explains the higher weight loss numbers in trials

Astra Labs supplies research compounds strictly for laboratory research use only