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Given the multifactorial nature of PCOS, therapeutic approaches require personalized strategies rather than single-modality interventions

The novel dipeptidyl peptidase-4 inhibitor teneligliptin prevents high-fat diet-induced obesity accompanied with increased energy expenditure in mice

**DREAMS-1 Phase 3 Study** The DREAMS-1 Phase 3 study was a randomized, double-blind, placebo-controlled study that investigated the efficacy and safety of Mazdutide in Chinese patients with type 2 diabetes

Loss of appetite: due to the mechanisms of action, loss of appetite is also a common side effect

2023;151:e2022060640

Tricyclic antidepressants (amitriptyline/trimipramine) and glucose homoeostasis implications of insulin resistance
