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Description
A key upregulation was found in the polymeric immunoglobulin receptor gene (PIGR), known to increase the risk of inflammatory bowel disease

Studies have shown that sudden discontinuation can cause appetite and metabolism to shift quickly, which increases the chance of regaining weight

Shapely is a personalized weight loss program in Los Angeles, California that takes a whole-person approach to losing weight and keeping it off

10.1186/s12933-018-0769-x [EL 2

There is a need for prospective studies and controlled trials for more concrete evidence

In the TRIUMPH-1 trial, participants on the highest dose (12 mg) lost an average of 70.3 lbs (28.3%) over 80 weeks, with 65.3% achieving a BMI below 30
