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GLP-1RA use was associated with a reduced risk of adverse outcomes in the full cohort (hazard ratio [HR] 0.79, 95% CI 0.66-0.96), and in UC (HR 0.73, 95% CI 0.54-0.98), though not significantly in CD (HR 0.86, 95% CI 0.66-1.08)

These variables were selected based on their associations with both GLP-1 receptor agonist treatment and major adverse cardiovascular events, as reported in the literature

Lower cost + no injections = mass adoption

Increase your fibre intake along with water

This medication is also used to help lower the risk of various cardiovascular diseases and worsening kidney disease (in patients with chronic kidney disease and type 2 diabetes)

Methods In this retrospective cohort study, 125 474 adults with overweight or obesity newly initiated treatment with a dual-labeled GLP-1 RA (liraglutide, semaglutide, or tirzepatide) between January 1, 2018, and December 31, 2023, with a baseline body mass index of 27 or more, an available weight measurement within 60 days before initiation, and regular care in the year before initiation were identified using electronic health record data from a collective of US health care systems