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Lancet Diabetes Endocrinol 2014;2:3037 [DOI] [PubMed] [Google Scholar] 180
Persistent high glucose levels have been linked to decreased testosterone levels, in part due to the downregulation of vascular endothelial growth factor (VEGF), which compromises testicular microcirculation, leading to Leydig cell dysfunction and blunted testosterone synthesis [64]
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