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The first encouraging human signal came from Athauda and colleagues in 2017

According to the SURMOUNT-1 clinical trial, patients using tirzepatide at the highest dose (15 mg weekly) experienced up to 22.5% total body weight loss over 72 weeksgreater than what is typically seen with semaglutide GLP-1

The study used the Massachusetts General Hospital-Sexual Functioning Questionnaire (MGH-SFQ) to assess sexual desire in 24 volunteers, ages 18 to 50

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"This is a major step forward for patients with obstructive sleep apnea." "Today, many cases of OSA go undiagnosed and untreated, leaving millions at risk for serious health consequences," added Patrik Jonsson, president of Lilly Cardiometabolic Health and Lilly USA