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The medication is available in multiple formulations to accommodate different patient needs and treatment protocols, with dosing typically following a gradual titration approach to optimize therapeutic benefits while minimizing adverse effects

The SURMOUNT trials demonstrated that blood pressure effects occur in this population, with magnitude often correlating to degree of weight loss

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The medication is not approved by the FDA

One meta-analysis compared the highest dose of tirzepatide (15 mg) to the highest dose of semaglutide (2 mg) and found that tirzepatide resulted in a greater weight loss at a 17.8% reduction in body weight versus 12.4% for semaglutide

Do not take a higher dose thinking it will "carry you through" the washout