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The molecular mechanism of tamoxifen activity in macrophages was initially associated with the activation of PKC and transcription factors, such as GR, PPARy and STAT1 ( Differently from cytotoxicity in epithelial or hepatic cells, off-target effects of tamoxifen do not induce macrophage cell death

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10.1126/science.aag2590 67 Salvador Andrea FrancescaM.KipnisJonathan

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