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[DOI] [PMC free article] [PubMed] [Google Scholar] 138.Lee Y.S., Park M.S., Choung J.S., Kim S.S., Oh H.H., Choi C.S., Ha S.Y., Kang Y., Kim Y., Jun H.S

Nature 612 , 720724 (2022)

When patients specifically switched from semaglutide to tirzepatide , they continued losing weight

M., Jung, H

Common and potential side effects include: Skin irritation : Redness, itching, rashes, or allergic reactions where the patch sits, especially with daily use Cardiovascular effects : Bitter orange extract can increase heart rate and blood pressure Digestive issues : Green tea extract may cause upset stomach or headaches Sleep problems : Caffeine content from green tea extract can disrupt sleep Liver concerns : Garcinia cambogia has been linked to liver problems in some cases Unknown risks : Lack of regulation means uncertain ingredient quality and quantities The bigger concern is that these products arent regulated in the same way as prescription medications