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Missing even one dose monthly reduces total weight loss by 2-3 percentage points over 6-12 months

For the thigh, most people have sufficient subcutaneous fat to inject without pinching

But delayed gastric emptying also affects how quickly oral medications are absorbed

Last reviewed: June 28, 2026 Last updated: June 28, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

For those in California, tirzepatide injections offer a science-backed solution to weight loss