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In placebo-controlled trials, severe GI reactions were reported in 1.7% (5 mg), 2.5% (10 mg), and 3.1% (15 mg) of Zepbound-treated patients compared to 1% of placebo-treated patients

Additionally, it affects a broader population, including non-diabetic individuals using these medications for weight loss

Data shown as the mean SEM

Shared Decision-Making : Treatment decisions should involve the adolescent, their family, and a multidisciplinary healthcare team

Further research must be conducted on the additional potential benefits of DPP-4 inhibitors before the recommendation for DPP-4 inhibitors over SGLT2 inhibitors or GLP-1 agonists as a second-line agent for patients with type 2 diabetes can be strengthened

It really helps kickstart my mornings and keeps me motivated to stay active