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Diabetes also increases the morbidity and mortality of these patients, by contributing to higher rates of infections, cardiovascular events, and malignancy

GLP-1 regulates blood sugar by stimulating insulin release and inhibiting glucagon secretion

For patients requiring triple therapy, GLP-1 receptor agonists can be combined with metformin and a sodiumglucose cotransporter 2 inhibitor in patients with persistent hyperglycemia

These typically improve over time, especially with gradual dose escalation

At the 52-week mark, RYBELSUS continued to shine, demonstrating a statistically significant advantage in A1C reduction over Januvia

Snitman contacted Diabetes Canada, saying he felt he got sucked in by seeing their logo on the ad