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The more meaningful question is not: Do patients regain weight after stopping GLP-1s? It is: How should we transition patients from pharmacologic support to long-term weight maintenance? Obesity is a chronic disease

dosage format

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This mechanism is similar to existing GLP-1 receptor agonists like semaglutide or liraglutide, which are used to treat obesity and diabetes

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This review also highlights a possible crosstalk between autophagy and the GLP-1/GLP-1R axis in the treatment of diabetic angiopathy.