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Description
More complicated molecular modifications that led to the approval of once-weekly products include fusing either recombinant human serum albumin (Tanzeum) or an antibody fragment crystallizable (Fc) moiety (Trulicity) to a GLP-1 analog
107 Further, serious risks associated with Tanzeum use include pancreatitis, acute kidney injury, renal impairment, and pneumonia, further limiting its use in specific conditions or susceptible patients

How to start the therapy

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4951,56 Orforglipron achieved even greater reductions, lowering HbA1c by up to 2.1% and weight by up to 10.1 kg

The bigger picture This approval does not end the GLP-1 story
