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Most studies investigating the effects of GLP-1 RAs on the human gut microbiota have been conducted in patients with T2D

Both drug classes demonstrate cardiovascular benefits, with SGLT2 inhibitors particularly effective for heart failure and GLP-1 receptor agonists reducing major adverse cardiovascular events

Effect of dapagliflozin on urinary albumin excretion in patients with chronic kidney disease with and without type 2 diabetes: a prespecified analysis from the DAPA-CKD trial

While Semaglutide GLP-1 is generally well-tolerated by most patients, it does have potential side effects, including nausea, vomiting, abdominal pain, and diarrhea

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At the same time, these medications slow how quickly food leaves your stomach, which reduces sudden spikes in blood sugar and helps prevent the rapid return of hunger