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Because these existing drugs are not universally effective, medical professionals have actively searched for alternative approaches

From a pharmacological perspective, tirzepatide acts primarily through GIP and GLP-1 receptor pathways to modulate insulin secretion, glucagon suppression, and appetite regulation

Acknowledgements Not applicable

Initially, it was meant to bind with the pancreas
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Targeting inflammation for the treatment of Diabetic Kidney Disease: a five-compartment mechanistic model
