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Mir Ali, medical director at MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center, California

Many people combine GLP-1 agonists with GH peptides like tesamorelin or ipamorelin

It simultaneously activates GLP-1, GIP, and glucagon receptors a mechanism that distinguishes it from approved agents such as semaglutide and tirzepatide

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While diabetic ketoacidosis (DKA) is rare in type 2 diabetes with adequate insulin production, uncontrolled blood sugar increases the risk of both acute complications and long-term microvascular and macrovascular damage

The stress of significant caloric deficit can shift hair follicles into resting phase, causing increased shedding 2-4 months after weight loss begins