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This activity of GLP-1 has been demonstrated in both preclinical and clinical studies, and the results support the hypothesis that the GLP-1 pathway regulates the processes of alcohol use disorder (AUD)

doi: 10.2337/db10-1185

Additionally, semaglutide has been shown to reduce the risk of heart attack and stroke

This has important clinical relevance since obese and diabetic populations have been reported to have higher prevalences of NENs, implicating that such a treatment may be even more accessible and appropriate for these unique cohorts [35,36,37,38]

Throughout the study, significant reductions in HbA 1c from baseline were observed for the treatment groups, with the greatest decreases occurring in patients with the higher baseline HbA 1c levels

The pattern people find most confusing here is that the loss is not linear