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PPAR2 is primarily expressed in adipose tissue and promotes the differentiation and proliferation of adipocytes, which are derived from fibroblasts, resulting in an increase in adiposity [26]

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Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been pivotal for obesity treatment, achieving 1525 % weight loss over 1224 months, but questions remain about the potential influence of concomitant losses in muscle mass

Sustained liraglutide administration for 3 weeks increases urinary sodium excretion independent of changes in ANP or blood pressure in overweight and obese hypertensive patients with type 2 diabetes 22

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