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Although there is a correlation between the two variables, it is not significant enough to draw any definite conclusions about the existence of a small-study effect based on this analysis alone (p-value = 0.485 for the slope)
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GLP-1 is a 30-amino acid peptide hormone produced by differential post-translational processing of the proglucagon precursor protein by prohormone convertase 1/3 (PCSK1) in intestinal L-cells and in neurons of the nucleus tractus solitarii (NTS) in the brainstem
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9.3 Application of the framework to peptide systems reviewed herein Applying this framework to the peptide systems discussed in this review clarifies their translational status
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oral semaglutide reductions were significant vs placebo (dosage-dependent estimated treatment difference [ETD] range for oral semaglutide vs placebo, -0.4% to -1.6%
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Metabolic changes that may slow down without the medications effects
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