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Description
Methods SURMOUNT-2 participants were randomly assigned (1:1:1) to receive either tirzepatide 10 mg (n=312), tirzepatide 15 mg (n=311), or placebo (n=315) for 72 weeks as an adjunct to diet and exercise
The use of GLP-1RA is a new therapeutic strategy that addresses both metabolic and cognitive/neuropsychiatric aspects, which is fundamentally important for the treatment of comorbid diseases.
In clinical trials, it led to a weight reduction of up to 16.2%
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Tirzepatide targets both GLP-1 and GIP receptors, potentially offering greater metabolic and ovulation benefits in PCOS
