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There's also data suggesting that in some cases, people who take GLP-1s for several years can start to experience a waning effect - perhaps a drug resistance - where they start to regain some weight, even while taking the medication

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- : Liraglutide biosimilars are already showing promising early results, with several under investigation

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A new study has revealed that most Australian women of reproductive age prescribed GLP-1 receptor agonists are not using effective contraception, despite known risks during pregnancy.