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Clinical Significance: The 2025 updates reaffirm that while HbA1c remains central, a one-number-fits-all strategy is outdated

for severe obesity and Type 2 diabetes, the entry of low-cost generic versions has led to widespread misuse via online pharmacies and wellness clinics.

Not intended for pregnant or nursing mothers or children under the age of 18. Individuals taking blood thinners, any other medications, or have any known medical conditions should consult a physician before using any herbal supplements

This issue of the HPCs DataPoints series explores trends in GLP-1 prescriptions in Massachusetts through September 2023 and examines the use and spending impacts of these drugs in the Commonwealth.

These medications also delay gastric emptying through neural mechanisms, increasing the risk for perioperative aspiration during anaesthesia and sedation