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Description
The first residue in the loop is the site of a known SNP (Gly to Ser), but the simulated mutation had no effect on GLP-1 action (Koole et al., 2011)
Epac proteins: Multi-purpose cAMP targets

A study limitation was the number of participants (although similar studies assessing GLP-1 involved 15-16 participants)

Cogen, A

Taken together, these results indicate potential antidiarrheal effects of the GLP-1 nanomedicine

We found that the main enzymes of BCAA catabolism in cardiomyocytes and fibroblasts were upregulated after semaglutide treatment, indicating an improved catabolism of BCAAs
