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Its triple-receptor mechanism, targeting three hormone systems in the body, offers enhanced weight loss and metabolic benefits

Neuropharmacology 76 (Pt A), 5767

People treated with a high dose lost an average of 24 percent of their body weight after nearly a year of treatment, a small clinical trial reported this year

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Dulaglutide, another GLP-1RA, was found to suppress the proportion of pathogenic Th1 and Th17 cells and inhibit the secretion of granulocyte-macrophage colony-stimulating factor (GM-CSF) by Th1 cells within the CNS of EAE mice, resulting in improved clinical outcomes [268]

In addition, mice overexpressing GLP-1R in the hippocampus has shown an increase in neurite growth and improvement in spatial learning abilities (75)