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GDMT for HFrEF typically includes evidence-based beta-blockers, angiotensin receptor neprilysin inhibitors (ARNIs), angiotensin receptor blockers (ARBs), angiotensin-converting enzyme (ACE) inhibitors, mineralocorticoid receptor antagonists (MRA), and sodium-glucose cotransporter 2 inhibitors (SGLT2is), particularly in patients with obesity or T2DM [53]

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Green has been voted one of New York Citys best dermatologists by publications such as Castle Connolly, New York Magazine, and Super Doctors
(2) Up-titration of dexmedetomidine takes some time, so it may not be an ideal agent for the patient with profoundly dangerous agitation
