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Efficacy and Safety of Glucagon-Like Peptide-1/Glucagon Receptor Co-Agonist JNJ-64565111 in Individuals With Obesity Without Type 2 Diabetes Mellitus: A Randomized Dose-Ranging Study

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The high cost disproportionately excludes those who might need it most: people with obesity-related disabilities, low-income patients with high comorbidity burdens, or those struggling with mobility

Headaches can occur, particularly during the initial titration phase or during rapid weight loss

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This makes them an attractive option for diabetes management, particularly for those who are overweight or obese