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doi: 10.3389/fimmu.2018.01291 15 GrahamDLMadkourHSNobleBLSchatschneiderCStanwoodGD

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17,25 However, some structures, such as circumventricular organs (CVOs), lack a complete BBB

While this review focused on insulin, the findings apply to GLP-1 medications since both are temperature-sensitive peptide hormones requiring similar storage conditions