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At the level of adipose tissue, GIPR activation promotes fatty acid uptake during energy surplus and fatty acid release during energy deficit, effects that complement the appetite suppression driven by GLP-1R

Injecting into your left thigh on a day before an upper body workout, for example, avoids the discomfort of training a sore injection site

Administration and Availability Both Semaglutide (Ozempic, Wegovy) and Tirzepatide (Mounjaro, Zepbound) are available as once-weekly subcutaneous injections

This dual mechanism of action sets tirzepatide apart from other therapeutic agents, offering a more comprehensive approach to managing metabolic disorders

Dispose of unused materials according to institutional biosafety guidelines and applicable regulations

Meanwhile, tirzepatide is also being evaluated in another large-scale cardiovascular outcomes trial, SURMOUNT-MMO