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Halloum et al

Production of hydrogen sulfide by the intestinal microbiota and epithelial cells and consequences for the colonic and rectal mucosa

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As a result, the long-acting GLP-1 agonists may cause a decrease of body weight by 25 kg on average

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For diabetes management, the target HbA1c is typically below 7% for most adults, though individualized targets may be appropriate based on age, comorbidities, and hypoglycemia risk