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In these cases, do not re-inject

In this context, it has been demonstrated that treatments with either a GLP1/Estrogen (GLP1/E) conjugate, a unimolecular GLP1/GIP (gastric inhibitory peptide) dual agonist, or a GLP1/GIP/Glucagon triagonist, markedly reduced body weight and improved diabetic complications, including hyperinsulinemia, in preclinical models of obesity in males 33,34,35

His average systolic blood pressure improved from ~170 to ~140 despite discontinuation of his antihypertensive regimen, and his chronic non-healing leg wound resolved without antibiotics

Individual experiences can vary widely with these medicines

Switch to insulin or metformin

Approved Alternatives Available Through NHS and Private Clinics MHRA-approved options include semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro), both recommended by NICE for weight management within specialist services under defined eligibility criteria