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A review of head-to-head clinical trials comparing key outcomes of using GLP-1RAs (dulaglutide, exenatide BD, exenatide QW, liraglutide or lixisenatide) with those of using DPP-IV (sitagliptin), SU (glimepiride

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Still, participants saw weight losses that are larger than most exercise-only programs can deliver

remains investigational rather than an approved therapy

Similarly, liraglutide treatment significantly reduced LPS-induced upregulation of Il-6 , Cox2 , and Tnf- in RAW 264.7 cells ( p = 0.0286 compared to LPS group) in a dose-dependent manner (Fig