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For someone needing substantial weight loss, prescription GLP-1 agonists provide far superior effectiveness to any natural alternative

It depends and the answer is changing fast

N Engl J Med 377:644657 Wiviott SD, Raz I, Bonaca MP, Mosenzon O, Kato ET, Cahn A, Silverman MG, Zelniker TA, Kuder JF, Murphy SA, Bhatt DL, Leiter LA, McGuire DK, Wilding JPH, Ruff CT, Gause-Nilsson IAM, Fredriksson M, Johansson PA, Langkilde AM, Sabatine MS (2019) Dapagliflozin and cardiovascular outcomes in type 2 diabetes

Preclinical studies in rodent models have consistently demonstrated that GLP-1 receptor agonists reduce voluntary alcohol intake and preference

How Clinics Can Boost Patient Compliance with GLP1

However, those who aren't eligible after testing as well as those who can no longer afford medication are able to cancel