downsides to glp 1 GLP-1: The Diabetes Drug Changing How We Think About Weight Loss Glucagon-like Receptor-1 agonists for obesity:

Always use the back of the upper arm where fatty tissue is most abundant

Long-term inflammation is linked to: Type 2 diabetes Heart disease Fatty liver (NAFLD/NASH) Obesity Autoimmune and gut disorders Experts believe metabolic inflammation is a root cause of insulin resistance and poor cardiovascular outcomes

If you feel a firm lump under the skin at a previous injection site, do not inject into it or near it

These associations were independent of glycemic control and suggest a potential protective role of GLP-1 signaling in individuals with comorbid metabolic and alcohol-related disorders [76]

You dont see muscle loss on a bathroom scale

GLP-1 RAs have also demonstrated cardioprotective effects by reducing the risk of major cardiovascular events, such as heart attacks and strokes, in individuals with T2DM