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Most insurance plans cover the diabetes versions, but insurers often restrict access to the weight-loss versions

Sublingual daily dosing largely eliminates this problem

The recommended maintenance dosages of ZEPBOUND in adults are 5 mg, 10 mg, or 15 mg injected subcutaneously once weekly

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For someone with an A1C of 8.5%, tirzepatide 15mg could potentially bring that below 6.5%, which is below the diagnostic threshold for diabetes

Another relevant consideration is that animals were maintained at 90% body weight through mild food restriction, which alters baseline levels of appetite-regulatory peptides (Hayes et al