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Rodriguez et al., 2025), with those without T2DM exhibiting even higher rates of discontinuation than those with T2DM (Rodriguez et al., 2025)

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Novo Nordisk's oral version of its obesity injection Wegovy could enter the market by year-end, while Eli Lilly's pill orforglipron could launch next year

GLP-1 receptors exist on immune cells, and receptor activation appears to modulate inflammatory pathways

For those who had been on GLP-1RA medications for two or more years , the risk dropped but was still 1.27 times higher

Int Immunopharmacol 145:113730 Malvandi AM, Loretelli C, Ben Nasr M, Zuccotti GV, Fiorina P (2019) Sitagliptin favorably modulates immune-relevant pathways in human beta cells