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Novo Nordisk has innovated a subcutaneous formulation of semaglutide, branded as Ozempic, which functions as a modified human glucagon-like peptide-1 (GLP-1) analogue

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Heart disease remains a critical issue in men and women with diabetes.

GLP-1 and its synthetic analogs have emerged as significant therapeutic agents for the management of metabolic disorders, merging glycemic control with weight loss through innovative structural and delivery breakthroughs

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Patient-derived human islets from male and female cadaveric donors were 3D-cultured in solubilised extracellular matrix gel in co-culture with the same donor PBMCs, and incubated with cytokines (IL-1, TNF-, IFN-) for 2448 h in the presence of vehicle or increasing concentrations of the CB1R blocker JD-5037