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GLP-1 agonists work by stimulating appetite-suppressing neurons in the hypothalamus and slowing gastric emptying

Wegovy, a brand-name weight loss medication containing semaglutide, has taken the world by storm

Incretin therapies target the class B G protein-coupled receptors GLP-1R and GIPR, expressed mainly in the pancreas and the hypothalamus, while some therapeutical approaches include additional targeting of the related glucagon receptor (GCGR) in the liver

The variability in available studies, potential confounding factors, and the severe heterogeneity of conclusions all emphasize the need for more high-quality evidence-based primary research to optimize perioperative management of patients taking GLP-1 RAs

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How long does it take for semaglutide to show results