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How GLP-1 Drugs Cause Weight Loss GLP-1 drugs mimic a naturally occurring hormone called glucagon-like peptide-1 (GLP-1), which helps regulate appetite, blood sugar, and digestion

The FDA approved 3.0 mg and 4.5 mg doses of Trulicity, based on results from the AWARD-11 clinical trial

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Emerging research suggests GLP-1s may directly affect the skin by reducing collagen production, accelerating glycation (which stiffens and weakens collagen fibers), and diminishing hydration levels

Cold Stop: Which Approach Works Better Abruptly stopping Ozempic typically produces sharper appetite rebound than a gradual dose reduction