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Liraglutide attenuates the progression of hypertension in spontaneously hypertensive rats by activating brainstem dopamine beta-hydroxylase (DBH) neurons and suppressing sympathetic nerve activity [136]

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13 GLP-1 RA cardiovascular outcome trials 29 and head-to-head studies, 1529 with a follow-up range of 0.55.4 years, have documented that GLP-1 RAs increase heart rate by 0.15.7 b.p.m., with an average increase of 2.4 b.p.m

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