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GLP-1 receptor agonists, the class of drugs that includes semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound), are the most important class of medications to emerge in decades.

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Additional significant interactions were observed for all-cause death in females and in people with a history of smoking, alcohol use, heart failure, chronic kidney disease, or cholelithiasis
