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The researchers optimized the potency ratio between the three receptors and used a protraction strategy that allows for once-weekly dosing, then tested the drugs in diet-induced obese mice

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[DOI] [PMC free article] [PubMed] [Google Scholar] [179].Yiangou A, Mitchell JL, Vijay V, Grech O, Bilton E, Lavery GG, et al

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