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Outcomes vary individually

If the label includes a titration caution or if community physicians default to the 4 mg or 8 mg maintenance dose out of caution, the population-average weight loss Retatrutide actually produces could compress meaningfully below the 28.7% headline

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Dosing needs to be precise, and your heart and kidney health must be monitored by a professional

Other GLP-1R, GIPR, and glucagon receptor (GCGR) poly-agonists are in development and have been tested in phase 1 and phase 2 clinical trials, including GLP-1R/GCGR agonists, GLP-1R/GLP-2R agonists, and triple GLP-1R/GIPR/GCGR agonists (abstracts presented at the American Diabetes Association Annual Meeting in June, 2022 and (7))