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Moderate activity (walking, resistance training) three to four times weekly increases calorie deficit without demanding the energy levels that appetite-suppressed patients may lack

A 2017 clinical trial in 36 obese and overweight adults reached a similar conclusion: slow weight loss preserved more fat-free mass and resting metabolic rate than rapid weight loss 5

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The timeline for results from GLP-1 injections can vary depending on individual factors, but many patients begin noticing a reduction in appetite and modest weight loss within the first few weeks of starting therapy