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First, the study population was limited to individuals with diabetes or obesity, which may restrict the generalizability of results to broader populations

Yang HY, Liu M, Sheng Y, Zhu L, Jin MM, Jiang TX et al (2022) All-trans retinoic acid impairs glucose-stimulated insulin secretion by activating the RXR/SREBP-1c/UCP2 pathway

It is important to note that there is no official link established between Wegovy and worsening of autoimmune thyroid disease

[DOI] [PubMed] [Google Scholar] 15.Pratley R.E., Aroda V.R., Lingvay I., et al

However, this evidence is limited, inconsistent, and does not demonstrate clinically significant effects comparable to prescription GLP-1 agonists

Sarcopenia is a cause and consequence of metabolic dysregulation in aging humans: effects of gut dysbiosis, glucose dysregulation, diet and lifestyle