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Vital Sign and Electrocardiogram (EGC) Changes No clinically meaningful changes in vital signs or in ECG (including in QTc interval) were observed in patients treated with sitagliptin Laboratory Tests Across clinical trials, the incidence of laboratory adverse reactions was similar in patients treated with sitagliptin 100 mg compared to patients treated with placebo

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^ Murage EN, Gao G, Bisello A, Ahn JM

The relationship is not definitively established as causal

Step 2: 5 hours before arrival time Drink entire second bottle